Clinical diagnostic criteria for dementia associated with Parkinson's disease
Identifieur interne : 000678 ( Main/Corpus ); précédent : 000677; suivant : 000679Clinical diagnostic criteria for dementia associated with Parkinson's disease
Auteurs : Murat Emre ; Dag Aarsland ; Richard Brown ; David J. Burn ; Charles Duyckaerts ; Yoshikino Mizuno ; Gerald Anthony Broe ; Jeffrey Cummings ; Dennis W. Dickson ; Serge Gauthier ; Jennifer Goldman ; Christopher Goetz ; Amos Korczyn ; Andrew Lees ; Richard Levy ; Irene Litvan ; Ian Mckeith ; Warren Olanow ; Werner Poewe ; Niall Quinn ; Christina Sampaio ; Eduardo Tolosa ; Bruno DuboisSource :
- Movement Disorders [ 0885-3185 ] ; 2007-09-15.
English descriptors
Abstract
Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society
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DOI: 10.1002/mds.21507
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Burn</name><affiliation><mods:affiliation>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle upon Tyne, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Duyckaerts, Charles" sort="Duyckaerts, Charles" uniqKey="Duyckaerts C" first="Charles" last="Duyckaerts">Charles Duyckaerts</name><affiliation><mods:affiliation>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Mizuno, Yoshikino" sort="Mizuno, Yoshikino" uniqKey="Mizuno Y" first="Yoshikino" last="Mizuno">Yoshikino Mizuno</name><affiliation><mods:affiliation>Department of Neurology, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</mods:affiliation></affiliation><affiliation><mods:affiliation>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</mods:affiliation></affiliation></author><author><name sortKey="Broe, Gerald Anthony" sort="Broe, Gerald Anthony" uniqKey="Broe G" first="Gerald Anthony" last="Broe">Gerald Anthony Broe</name><affiliation><mods:affiliation>Ageing Research Centre, Prince of Wales Hospital, Randwick, New South Wales, Australia</mods:affiliation></affiliation><affiliation><mods:affiliation>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales, Randwick, New South Wales, Australia</mods:affiliation></affiliation></author><author><name sortKey="Cummings, Jeffrey" sort="Cummings, Jeffrey" uniqKey="Cummings J" first="Jeffrey" last="Cummings">Jeffrey Cummings</name><affiliation><mods:affiliation>Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA</mods:affiliation></affiliation></author><author><name sortKey="Dickson, Dennis W" sort="Dickson, Dennis W" uniqKey="Dickson D" first="Dennis W." last="Dickson">Dennis W. Dickson</name><affiliation><mods:affiliation>Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, USA</mods:affiliation></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation><mods:affiliation>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging, Montreal, Quebec, Canada</mods:affiliation></affiliation></author><author><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name><affiliation><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</mods:affiliation></affiliation></author><author><name sortKey="Goetz, Christopher" sort="Goetz, Christopher" uniqKey="Goetz C" first="Christopher" last="Goetz">Christopher Goetz</name><affiliation><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</mods:affiliation></affiliation></author><author><name sortKey="Korczyn, Amos" sort="Korczyn, Amos" uniqKey="Korczyn A" first="Amos" last="Korczyn">Amos Korczyn</name><affiliation><mods:affiliation>Department of Neurology, Tel‐Aviv University, Ramat ‐Aviv, Israel</mods:affiliation></affiliation></author><author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name><affiliation><mods:affiliation>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Levy, Richard" sort="Levy, Richard" uniqKey="Levy R" first="Richard" last="Levy">Richard Levy</name><affiliation><mods:affiliation>Federation de Neurologie, INSERM U.610, AP‐HP, Groupe Hospitalier Pitié‐Salpetriere, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name><affiliation><mods:affiliation>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky, USA</mods:affiliation></affiliation></author><author><name sortKey="Mckeith, Ian" sort="Mckeith, Ian" uniqKey="Mckeith I" first="Ian" last="Mckeith">Ian Mckeith</name><affiliation><mods:affiliation>Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Olanow, Warren" sort="Olanow, Warren" uniqKey="Olanow W" first="Warren" last="Olanow">Warren Olanow</name><affiliation><mods:affiliation>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine, New York, USA</mods:affiliation></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation><mods:affiliation>Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria</mods:affiliation></affiliation></author><author><name sortKey="Quinn, Niall" sort="Quinn, Niall" uniqKey="Quinn N" first="Niall" last="Quinn">Niall Quinn</name><affiliation><mods:affiliation>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Sampaio, Christina" sort="Sampaio, Christina" uniqKey="Sampaio C" first="Christina" last="Sampaio">Christina Sampaio</name><affiliation><mods:affiliation>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Lisboa, Portugal</mods:affiliation></affiliation></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><affiliation><mods:affiliation>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona, Spain</mods:affiliation></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation><mods:affiliation>INSERM U610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, Paris, France</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:359A36465DC9552440E3F7D99EB22D4878A67D06</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/mds.21507</idno><idno type="url">https://api.istex.fr/document/359A36465DC9552440E3F7D99EB22D4878A67D06/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000678</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Clinical diagnostic criteria for dementia associated with Parkinson's disease</title><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name><affiliation><mods:affiliation>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Ístanbul Faculty of Medicine, Ístanbul University, Ístanbul, Turkey</mods:affiliation></affiliation></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><affiliation><mods:affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway</mods:affiliation></affiliation><affiliation><mods:affiliation>School of Medicine, University of Bergen, Norway</mods:affiliation></affiliation></author><author><name sortKey="Brown, Richard" sort="Brown, Richard" uniqKey="Brown R" first="Richard" last="Brown">Richard Brown</name><affiliation><mods:affiliation>King's College, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Burn, David J" sort="Burn, David J" uniqKey="Burn D" first="David J." last="Burn">David J. Burn</name><affiliation><mods:affiliation>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle upon Tyne, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Duyckaerts, Charles" sort="Duyckaerts, Charles" uniqKey="Duyckaerts C" first="Charles" last="Duyckaerts">Charles Duyckaerts</name><affiliation><mods:affiliation>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Mizuno, Yoshikino" sort="Mizuno, Yoshikino" uniqKey="Mizuno Y" first="Yoshikino" last="Mizuno">Yoshikino Mizuno</name><affiliation><mods:affiliation>Department of Neurology, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</mods:affiliation></affiliation><affiliation><mods:affiliation>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</mods:affiliation></affiliation></author><author><name sortKey="Broe, Gerald Anthony" sort="Broe, Gerald Anthony" uniqKey="Broe G" first="Gerald Anthony" last="Broe">Gerald Anthony Broe</name><affiliation><mods:affiliation>Ageing Research Centre, Prince of Wales Hospital, Randwick, New South Wales, Australia</mods:affiliation></affiliation><affiliation><mods:affiliation>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales, Randwick, New South Wales, Australia</mods:affiliation></affiliation></author><author><name sortKey="Cummings, Jeffrey" sort="Cummings, Jeffrey" uniqKey="Cummings J" first="Jeffrey" last="Cummings">Jeffrey Cummings</name><affiliation><mods:affiliation>Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA</mods:affiliation></affiliation></author><author><name sortKey="Dickson, Dennis W" sort="Dickson, Dennis W" uniqKey="Dickson D" first="Dennis W." last="Dickson">Dennis W. Dickson</name><affiliation><mods:affiliation>Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, USA</mods:affiliation></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation><mods:affiliation>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging, Montreal, Quebec, Canada</mods:affiliation></affiliation></author><author><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name><affiliation><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</mods:affiliation></affiliation></author><author><name sortKey="Goetz, Christopher" sort="Goetz, Christopher" uniqKey="Goetz C" first="Christopher" last="Goetz">Christopher Goetz</name><affiliation><mods:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</mods:affiliation></affiliation></author><author><name sortKey="Korczyn, Amos" sort="Korczyn, Amos" uniqKey="Korczyn A" first="Amos" last="Korczyn">Amos Korczyn</name><affiliation><mods:affiliation>Department of Neurology, Tel‐Aviv University, Ramat ‐Aviv, Israel</mods:affiliation></affiliation></author><author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name><affiliation><mods:affiliation>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Levy, Richard" sort="Levy, Richard" uniqKey="Levy R" first="Richard" last="Levy">Richard Levy</name><affiliation><mods:affiliation>Federation de Neurologie, INSERM U.610, AP‐HP, Groupe Hospitalier Pitié‐Salpetriere, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name><affiliation><mods:affiliation>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky, USA</mods:affiliation></affiliation></author><author><name sortKey="Mckeith, Ian" sort="Mckeith, Ian" uniqKey="Mckeith I" first="Ian" last="Mckeith">Ian Mckeith</name><affiliation><mods:affiliation>Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Olanow, Warren" sort="Olanow, Warren" uniqKey="Olanow W" first="Warren" last="Olanow">Warren Olanow</name><affiliation><mods:affiliation>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine, New York, USA</mods:affiliation></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation><mods:affiliation>Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria</mods:affiliation></affiliation></author><author><name sortKey="Quinn, Niall" sort="Quinn, Niall" uniqKey="Quinn N" first="Niall" last="Quinn">Niall Quinn</name><affiliation><mods:affiliation>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom</mods:affiliation></affiliation></author><author><name sortKey="Sampaio, Christina" sort="Sampaio, Christina" uniqKey="Sampaio C" first="Christina" last="Sampaio">Christina Sampaio</name><affiliation><mods:affiliation>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Lisboa, Portugal</mods:affiliation></affiliation></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><affiliation><mods:affiliation>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona, Spain</mods:affiliation></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation><mods:affiliation>INSERM U610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, Paris, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-09-15">2007-09-15</date><biblScope unit="volume">22</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="1689">1689</biblScope><biblScope unit="page" to="1707">1707</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">359A36465DC9552440E3F7D99EB22D4878A67D06</idno><idno type="DOI">10.1002/mds.21507</idno><idno type="ArticleID">MDS21507</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>Parkinson's disease dementia</term><term>dementia</term><term>diagnosis</term><term>diagnostic criteria</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Murat Emre MD</name><affiliations><json:string>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Ístanbul Faculty of Medicine, Ístanbul University, Ístanbul, Turkey</json:string></affiliations></json:item><json:item><name>Dag Aarsland MD</name><affiliations><json:string>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway</json:string><json:string>School of Medicine, University of Bergen, Norway</json:string></affiliations></json:item><json:item><name>Richard Brown PhD</name><affiliations><json:string>King's College, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, London, United Kingdom</json:string></affiliations></json:item><json:item><name>David J. Burn MD</name><affiliations><json:string>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle upon Tyne, United Kingdom</json:string></affiliations></json:item><json:item><name>Charles Duyckaerts MD</name><affiliations><json:string>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679, Paris, France</json:string></affiliations></json:item><json:item><name>Yoshikino Mizuno MD</name><affiliations><json:string>Department of Neurology, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</json:string><json:string>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</json:string></affiliations></json:item><json:item><name>Gerald Anthony Broe MD</name><affiliations><json:string>Ageing Research Centre, Prince of Wales Hospital, Randwick, New South Wales, Australia</json:string><json:string>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales, Randwick, New South Wales, Australia</json:string></affiliations></json:item><json:item><name>Jeffrey Cummings MD</name><affiliations><json:string>Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA</json:string></affiliations></json:item><json:item><name>Dennis W. Dickson MD</name><affiliations><json:string>Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, USA</json:string></affiliations></json:item><json:item><name>Serge Gauthier MD</name><affiliations><json:string>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging, Montreal, Quebec, Canada</json:string></affiliations></json:item><json:item><name>Jennifer Goldman MD</name><affiliations><json:string>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</json:string></affiliations></json:item><json:item><name>Christopher Goetz MD</name><affiliations><json:string>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</json:string></affiliations></json:item><json:item><name>Amos Korczyn MD</name><affiliations><json:string>Department of Neurology, Tel‐Aviv University, Ramat ‐Aviv, Israel</json:string></affiliations></json:item><json:item><name>Andrew Lees MD</name><affiliations><json:string>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Richard Levy MD, PhD</name><affiliations><json:string>Federation de Neurologie, INSERM U.610, AP‐HP, Groupe Hospitalier Pitié‐Salpetriere, Paris, France</json:string></affiliations></json:item><json:item><name>Irene Litvan MD</name><affiliations><json:string>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky, USA</json:string></affiliations></json:item><json:item><name>Ian McKeith MD</name><affiliations><json:string>Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom</json:string></affiliations></json:item><json:item><name>Warren Olanow MD</name><affiliations><json:string>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine, New York, USA</json:string></affiliations></json:item><json:item><name>Werner Poewe MD</name><affiliations><json:string>Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria</json:string></affiliations></json:item><json:item><name>Niall Quinn MD</name><affiliations><json:string>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom</json:string></affiliations></json:item><json:item><name>Christina Sampaio MD, PhD</name><affiliations><json:string>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Lisboa, Portugal</json:string></affiliations></json:item><json:item><name>Eduardo Tolosa MD</name><affiliations><json:string>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona, Spain</json:string></affiliations></json:item><json:item><name>Bruno Dubois MD</name><affiliations><json:string>INSERM U610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, Paris, France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>dementia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease dementia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>diagnosis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>diagnostic criteria</value></json:item></subject><articleId><json:string>MDS21507</json:string></articleId><language><json:string>eng</json:string></language><abstract>Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society</abstract><qualityIndicators><score>7.412</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>5</keywordCount><abstractCharCount>1414</abstractCharCount><pdfWordCount>13408</pdfWordCount><pdfCharCount>87541</pdfCharCount><pdfPageCount>19</pdfPageCount><abstractWordCount>201</abstractWordCount></qualityIndicators><title>Clinical diagnostic criteria for dementia associated with Parkinson's 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disease</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>WILEY</p></availability><date>2007</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Clinical diagnostic criteria for dementia associated with Parkinson's disease</title><author><persName><forename type="first">Murat</forename><surname>Emre</surname></persName><roleName type="degree">MD</roleName><note type="correspondence"><p>Correspondence: Behavioral Neurology and Movement Disorders Unit, Department of Neurology, İstanbul Faculty of Medicine, İstanbul University, 34390 Çapa İstanbul, Turkey</p></note><affiliation>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Ístanbul Faculty of Medicine, Ístanbul University, Ístanbul, Turkey</affiliation></author><author><persName><forename type="first">Dag</forename><surname>Aarsland</surname></persName><roleName type="degree">MD</roleName><affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway</affiliation><affiliation>School of Medicine, University of Bergen, Norway</affiliation></author><author><persName><forename type="first">Richard</forename><surname>Brown</surname></persName><roleName type="degree">PhD</roleName><affiliation>King's College, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, London, United Kingdom</affiliation></author><author><persName><forename type="first">David J.</forename><surname>Burn</surname></persName><roleName type="degree">MD</roleName><affiliation>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle upon Tyne, United Kingdom</affiliation></author><author><persName><forename type="first">Charles</forename><surname>Duyckaerts</surname></persName><roleName type="degree">MD</roleName><affiliation>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679, Paris, France</affiliation></author><author><persName><forename type="first">Yoshikino</forename><surname>Mizuno</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</affiliation><affiliation>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</affiliation></author><author><persName><forename type="first">Gerald Anthony</forename><surname>Broe</surname></persName><roleName type="degree">MD</roleName><affiliation>Ageing Research Centre, Prince of Wales Hospital, Randwick, New South Wales, Australia</affiliation><affiliation>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales, Randwick, New South Wales, Australia</affiliation></author><author><persName><forename type="first">Jeffrey</forename><surname>Cummings</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA</affiliation></author><author><persName><forename type="first">Dennis W.</forename><surname>Dickson</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, USA</affiliation></author><author><persName><forename type="first">Serge</forename><surname>Gauthier</surname></persName><roleName type="degree">MD</roleName><affiliation>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging, Montreal, Quebec, Canada</affiliation></author><author><persName><forename type="first">Jennifer</forename><surname>Goldman</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation></author><author><persName><forename type="first">Christopher</forename><surname>Goetz</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation></author><author><persName><forename type="first">Amos</forename><surname>Korczyn</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, Tel‐Aviv University, Ramat ‐Aviv, Israel</affiliation></author><author><persName><forename type="first">Andrew</forename><surname>Lees</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation></author><author><persName><forename type="first">Richard</forename><surname>Levy</surname></persName><roleName type="degree">MD, PhD</roleName><affiliation>Federation de Neurologie, INSERM U.610, AP‐HP, Groupe Hospitalier Pitié‐Salpetriere, Paris, France</affiliation></author><author><persName><forename type="first">Irene</forename><surname>Litvan</surname></persName><roleName type="degree">MD</roleName><affiliation>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky, USA</affiliation></author><author><persName><forename type="first">Ian</forename><surname>McKeith</surname></persName><roleName type="degree">MD</roleName><affiliation>Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom</affiliation></author><author><persName><forename type="first">Warren</forename><surname>Olanow</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine, New York, USA</affiliation></author><author><persName><forename type="first">Werner</forename><surname>Poewe</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria</affiliation></author><author><persName><forename type="first">Niall</forename><surname>Quinn</surname></persName><roleName type="degree">MD</roleName><affiliation>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom</affiliation></author><author><persName><forename type="first">Christina</forename><surname>Sampaio</surname></persName><roleName type="degree">MD, PhD</roleName><affiliation>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Lisboa, Portugal</affiliation></author><author><persName><forename type="first">Eduardo</forename><surname>Tolosa</surname></persName><roleName type="degree">MD</roleName><affiliation>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona, Spain</affiliation></author><author><persName><forename type="first">Bruno</forename><surname>Dubois</surname></persName><roleName type="degree">MD</roleName><affiliation>INSERM U610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, Paris, France</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-09-15"></date><biblScope unit="volume">22</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="1689">1689</biblScope><biblScope unit="page" to="1707">1707</biblScope></imprint></monogr><idno type="istex">359A36465DC9552440E3F7D99EB22D4878A67D06</idno><idno type="DOI">10.1002/mds.21507</idno><idno type="ArticleID">MDS21507</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2007</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>dementia</term></item><item><term>Parkinson's disease dementia</term></item><item><term>diagnosis</term></item><item><term>diagnostic criteria</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article category</head><item><term>Review</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-02-19">Received</change><change when="2007-03-10">Registration</change><change when="2007-09-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/359A36465DC9552440E3F7D99EB22D4878A67D06/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. 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type="toTypesetVersion" href="file:MDS.MDS21507.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="3"></count><count type="referenceTotal" number="179"></count><count type="wordTotal" number="14771"></count></countGroup><titleGroup><title type="main" xml:lang="en">Clinical diagnostic criteria for dementia associated with Parkinson's disease</title><title type="short" xml:lang="en">Clinical Diagnostic Criteria for PD‐D</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Murat</givenNames><familyName>Emre</familyName><degrees>MD</degrees></personName><contactDetails><email>muratemre@superonline.com</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2 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Innsbruck, Austria</unparsedAffiliation></affiliation><affiliation xml:id="af22" countryCode="GB" type="organization"><unparsedAffiliation>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom</unparsedAffiliation></affiliation><affiliation xml:id="af23" countryCode="PT" type="organization"><unparsedAffiliation>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Lisboa, Portugal</unparsedAffiliation></affiliation><affiliation xml:id="af24" countryCode="ES" type="organization"><unparsedAffiliation>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona, Spain</unparsedAffiliation></affiliation><affiliation xml:id="af25" countryCode="FR" type="organization"><unparsedAffiliation>INSERM U610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, Paris, France</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Parkinson's disease</keyword><keyword xml:id="kwd2">dementia</keyword><keyword xml:id="kwd3">Parkinson's disease dementia</keyword><keyword xml:id="kwd4">diagnosis</keyword><keyword xml:id="kwd5">diagnostic criteria</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Clinical diagnostic criteria for dementia associated with Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Clinical Diagnostic Criteria for PD‐D</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Clinical diagnostic criteria for dementia associated with Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Murat</namePart><namePart type="family">Emre</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Ístanbul Faculty of Medicine, Ístanbul University, Ístanbul, Turkey</affiliation><description>Correspondence: Behavioral Neurology and Movement Disorders Unit, Department of Neurology, İstanbul Faculty of Medicine, İstanbul University, 34390 Çapa İstanbul, Turkey</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dag</namePart><namePart type="family">Aarsland</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway</affiliation><affiliation>School of Medicine, University of Bergen, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Richard</namePart><namePart type="family">Brown</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>King's College, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">David J.</namePart><namePart type="family">Burn</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle upon Tyne, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Charles</namePart><namePart type="family">Duyckaerts</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yoshikino</namePart><namePart type="family">Mizuno</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</affiliation><affiliation>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine, Bunkyo‐ku, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gerald Anthony</namePart><namePart type="family">Broe</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Ageing Research Centre, Prince of Wales Hospital, Randwick, New South Wales, Australia</affiliation><affiliation>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales, Randwick, New South Wales, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jeffrey</namePart><namePart type="family">Cummings</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dennis W.</namePart><namePart type="family">Dickson</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Serge</namePart><namePart type="family">Gauthier</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging, Montreal, Quebec, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jennifer</namePart><namePart type="family">Goldman</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christopher</namePart><namePart type="family">Goetz</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Amos</namePart><namePart type="family">Korczyn</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Tel‐Aviv University, Ramat ‐Aviv, Israel</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Andrew</namePart><namePart type="family">Lees</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Richard</namePart><namePart type="family">Levy</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Federation de Neurologie, INSERM U.610, AP‐HP, Groupe Hospitalier Pitié‐Salpetriere, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Irene</namePart><namePart type="family">Litvan</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ian</namePart><namePart type="family">McKeith</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Warren</namePart><namePart type="family">Olanow</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine, New York, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Werner</namePart><namePart type="family">Poewe</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Niall</namePart><namePart type="family">Quinn</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christina</namePart><namePart type="family">Sampaio</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Lisboa, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Eduardo</namePart><namePart type="family">Tolosa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Bruno</namePart><namePart type="family">Dubois</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>INSERM U610, Pavillon Claude Bernard, Hôpital de la Salpêtrière, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-09-15</dateIssued><dateCaptured encoding="w3cdtf">2007-02-19</dateCaptured><dateValid encoding="w3cdtf">2007-03-10</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">3</extent><extent unit="references">179</extent><extent unit="words">14771</extent></physicalDescription><abstract lang="en">Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>dementia</topic><topic>Parkinson's disease dementia</topic><topic>diagnosis</topic><topic>diagnostic criteria</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Review</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>no.</caption><number>12</number></detail><extent unit="pages"><start>1689</start><end>1707</end><total>19</total></extent></part></relatedItem><identifier type="istex">359A36465DC9552440E3F7D99EB22D4878A67D06</identifier><identifier type="DOI">10.1002/mds.21507</identifier><identifier type="ArticleID">MDS21507</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2007 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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